Because it was found that the threats of hormonal agent treatment exceeded the advantages, researchers have actually been looking for a safe, natural method to ease the signs of menopause.
Individuals are presently being hired for a follow-up medical trial of a treatment called MF101 established by Bionovo, Inc. In its preliminary scientific trial, MF101 offered females in the research study with initial proof of remedy for such signs as hot flashes and night sweats, without the dangers related to hormonal agent treatment.
The treatment being evaluated medically targets just one of the 2 recognized estrogen receptors-the estrogen receptor beta. Lab information has actually revealed that MF101 does not trigger the expansion of breast or uterine cancer cells the method hormonal agent treatment can, making the drug a more secure option to presently offered hormonal agent treatments.
In 2002, the Women’s Health Initiative (WHI) Estrogen Plus Progestin Trial, with over 16,000 ladies individuals, was stopped early when it was discovered that the basic dosage of mix hormonal agent treatment increased the threat of breast cancer, stroke, cardiovascular disease, embolism and dementia.
“Given deep space that exists for a efficient and safe treatment for menopausal signs, our goal is to find and establish unique drugs such as MF101 that can ease off much of the signs that have actually traditionally been treated with hormonal agents,” stated Dr. Mary Tagliaferri. Tagliaferri is co-author of “The New Menopause Book: The Experts Help You Make Informed Decisions on HRT, Natural Hormone Therapy, Herbal Therapies, Traditional Chinese Medicine And More” (Avery, 2006) and Chief Medical Officer of Bionovo, which is establishing the drug.
The scientific trials will take location under the directorship of prominent scientist Dr. Deborah Grady at 4 leading scholastic medical.
Bionovo anticipates this Phase 2 trial to be finished by the 2nd quarter of 2007.
“If this brand-new drug shows to be reliable, we will be offering healthcare professionals with a treatment they can conveniently advise to females experiencing menopause,” stated Dr. Tagliaferri.